4-acetoxy DMT also known as deadhead chemist 4-Aco DMT is an O-acetylated psilocin that is believed to be a synthetic prodrug of psilocin, the psychedelic hallucinogen derived from various mushrooms. Although its pharmacological and toxicological properties are not well known, its activity has been proposed to be somewhat similar to that of psilocybin and psilocin. This product is intended for forensic and research applications.

Deadhead Chemist 4-AcO-DMT Dosage

Before I start to explain what tripping with deadhead chemist 4-AcO is like, it’s important to emphasize just how dose-dependent the research chemical is. The general consensus among users on message boards and the nine people who filled out a survey I created on 4-AcO, is that lower doses feel like a psilocybin experience, while higher doses start to more so resemble a DMT experience. Or as Sarah*, one of my survey participants, put it, “It was like mushrooms, DMT, and acid in one… like a long DMT trip with the warm and loving feeling of mushrooms, and the mind-blowing experience of acid.”

Deadhead chemist 4-AcO Dose Ranges for Oral Ingestion: 

• Microdose: 2.5 – 5 mg
• Low Dose: 5 – 10 mg
• Moderate Dose: 10 – 20 mg
• High Dose: 20 – 40 mg
• Heroic Dose: 40 mg +

As a general reference point, many say that oral doses in the 15 to 20 mg range greatly resemble a 3.5-gram magic mushroom experience and with all new psychedelics, it’s best to start with a low to moderate dose, or even microdose, for your first trip in order to get a lay of the land before diving into stronger experiences.

For nasal ingestion, doses will be slightly different because many folks report snorting the powder to be a stronger but possibly shorter acting experience. Also, one of my survey participants reported the powder can turn blue in your nostrils, so don’t be alarmed if this happens to you, as well.

Deadhead chemist 4-AcO Dose Ranges for Intranasal Ingestion:

• Microdose: less than 5 mg
• Low Dose: 5 – 10 mg
• Moderate Dose: 10 – 20 mg
• High Dose: 20 – 30 mg
• Heroic Dose: 30 mg +

For safe dosing, be sure to weigh out your dose on a scale that can read milligrams and if you don’t own one, you should consider investing. They don’t cost more than about $20 and are an easy way to practice harm reduction. Especially with research chemicals that come as powders, a small amount can have a big impact on the strength of the experience.

O-acetylpsilocin Duration

Most folks report an O-acetylpsilocin trip to last more or less the same amount of time as mushrooms but from four to eight hours with an afterglow lasting up to 48 hours after the experience has ended.

Psychonaut Wiki has mapped out the duration as such:

• Total: 4 – 7 hours
• Onset: 15 – 40 minutes
• Come Up: 30 – 75 minutes
• Peak: 2 to 3.5 hours
• Offset: 1 – 2 hours
• After effects: 4 – 48 hours

Deadhead Chemist 4-AcO DMT Trip 

The 4-AcO trip is very dose-dependent. The most common way people describe it is the trip being like a crisp, lucid, and warm mushroom experience on low and moderate doses of about 15 to 30 mg. “Deadhead chemist 4-AcO has a very light and joyous character, almost childlike. Like mushrooms but crisper and clearer,” wrote Steven*, one of my survey respondents, who’s tried 4-AcO at doses ranging from 10 to 50 mg several hundred times. “It’s slightly gentler and more simplified of a trip than mushrooms, but almost the same feeling.”